In clinical trials, tirzepatide has produced the following weight loss results:Tirzepatide is a new medication that was approved in May 2022 for Type 2 diabetes. INDIANAPOLIS, Nov. 4mg. The purified tirzepatide–GIPR–G s –Nb35 complex at a concentration of 18-20 mg/mL was mixed with 100 μM tirzepatide at 4 °C and applied to glow-discharged holey carbon grids (Quantifoil R1. Tirzepatide is sold for laboratory research use only. OrganizerBarbie. Tirzepatide, or LY3298176, is a unimolecular dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist that is under study for its glycemic control and weight loss benefits [1, 2, 3]. You can stay at this dose if the product is still. Select options. Tirzepatide is a 39-amino acid linear polypeptide which is conjugated to a C20 fatty diacid moiety via a linker connected to lysine -20. 3% (7. Warehouse Location. 5 mg once weekly. Tirzepatide - Here is the protocol and dosing for Tirzepatide “I” follow: Weeks 1-4: 2. It is estimated that 7. The primary end point was percentage change in body weight from baseline to week 72. 1). 1 It is a glucagon-like peptide-1 (GLP-1) receptor agonist with added glucose-dependent insulinotropic polypeptide (GIP). 5mg/week = 30mg. Native GIP and GLP-1 are incretin hormones that stimulate insulin secretion and decrease glucagon secretion. Tirzepatide is a combination of two drugs that work together to regulate blood glucose levels in a new and innovative way. What's important is when to increase your dose, how often you increase the dose, and when to dose the medication. Dimensions. In the phase 1 and phase 2 trials tirzepatide demonstrated dose-dependent reduction in HbA1c (up to 2. •In rats, tirzepatide causes thyroid C-cell tumors. I was wondering about purity so I had mine tested in a lab in Arizona and it came back 99. Tirzepatide injection is used to treat type 2 diabetes. 1mg x 10 Vials) 10mg (1mg x 10 Vials) IGF-1 LR3. Patients who used tirzepatide lost an average of 18 percent of their body weight, according to the F. 7% (34. Fax: 813-463-7830Tirzepatide is a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist approved for type 2 diabetes. 5 mg once-weekly and then increased the dose in a step-wise approach at four-week intervals to their final randomized maintenance dose of 5 mg (via a 2. 99 each and save 18%. Buy 5 for $149. Food and Drug Administration approved Zepbound (tirzepatide) injection for chronic weight management in adults with obesity (body mass. Tirzepatide (Mounjaro) is an FDA-approved weekly injection used for type 2 diabetes to lower blood sugar. Tirzepatide, a drug approved for the treatment of type 2 diabetes, could be on its way to becoming a new drug to treat obesity as well, now that the U. See moreWHAT IS TIRZEPATIDE? Tirzepatide (known by the brand name Mounjaro), is an injectable prescription medicine that is used. 1 Vial Sequence YXEGTFTSDYSIXLDKIAQKAFVQWLIAGGPSSGAPPPS (X2 and X13 are α-amino isobutyric acid (Aib), S39 is L-serinamide, and K20 is N6- {N- (hydrogen. 5mg once a week. 57% with 15-mg doses of tirzepatide. Tirzapatide is a glucagon-like peptide-1 (GLP-1) receptor agonist. 4 pounds (15. 25 of semaglutide bc I don’t wanna up my Tirzepatide dose. Here’s how the GLP-1 and GIP receptor agonist works, along with its potential benefits and side effects. 00 Select amount; Sale! Semaglutide $ 349. tirzepatide (20mg) is shown to lead to approximately 20% body weight loss. Tirzepatide, sold under the brand name Mounjaro, is a medication used for the treatment of type 2 diabetes. Tirzepatide has not been linked to elevations in serum aminotransferase levels during therapy or to episodes of clinically apparent liver. 4 lb. Over one-third of participants using tirzepatide. Tirzepatide is a glucose-dependent insulinotropic. hrt2015 • Hmm. Tirzepatide should be injected subcutaneously (under the skin) in the abdomen, thigh, or upper arm. Get free coupon. 3ml plus another 0. 9% pure. 5 mg, 5 mg, 7. The typical adult dosage for weight loss is based on the Wegovy (brand name semaglutide) prescribing guidelines at time of writing. This product is available in the following dosage forms:We would like to show you a description here but the site won’t allow us. Obesity is the most prevalent chronic disease worldwide, affecting approximately 650 million adults. INFORMATION. 4 mg has yet to be performed. Tirzepatide’s ability to co-administer GIP. Listen for the first click as the injection starts and the second click as the injection ends. 5 doses. S. Hello- I need help!Tirzepatide is a once-weekly dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that integrates the actions of both incretins into a single novel molecule. just below 30, on average. Tirzepatide Tizanidine Topiramate Ulipristal Valproic Acid Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Participants received subcutaneous injections of Tirzepatide or placebo once a week for 72 weeks. The authors found that tirzepatide 15 mg was the most efficacious in reducing HbA1c versus placebo (mean difference -2. This dual capability. Tirzepatide is a combination glucagon-like peptide 1 (GLP-1) receptor AND glucose-dependent insulinotropic polypeptide (GIP) receptor agonist that acts on areas of brain that regulate food intake and appetite. All Peptides are shipped non labeled. Tirzepatide is a Synthetic Derivative of The Gastric Inhibitory Polypeptide (GIP) that also has simultaneous Glucagon-Like Peptide-1 (GLP-1) functionality. 1mg (0. The first drug is a GLP-1 receptor agonist, which works by slowing the rate at which food leaves the stomach, increasing feelings of fullness, and increasing insulin secretion. 0 milligrams per week, while the therapeutic dose for Wegovy is 0. 5-mg increments after at least 4 weeks at current dose. Weeks 5-8: 3. It is a dual glucose -dependent insulinotropic polypeptide and glucagon -like peptide-1 agonist used for the management of type 2 diabetes mellitus. 32% with 10 mg and 5. Participants with obesity or overweight and type 2 diabetes taking tirzepatide lost up to 34. Conversely, tirzepatide 10 mg and 15 mg did not differ in the extent of body weight reduction. 31, 95% CI. The reductions in HbA1c observed for tirzepatide at 52 weeks were maintained after 78 weeks and 88 weeks of treatment with no increase in cardiovascular risk. • Tirzepatide causes thyroid C-cell tumors in rats. 5. Linebaugh Ave Tampa, FL 33624. 0 mg (-1. Tirzepatide, −7. Tirzepatide 10 mg and 15 mg demonstrated statistically significant reductions in SBP compared to GLP-1 RA, semaglutide 1 mg (5. **Don’t Forget the Sterile Water – Sold Here. VIEW MORE MEDICATIONS. 00%), followed by tirzepatide 10 mg (-1. For month 2, if you choose to titrate up your dosage, buy 4 vials for 1 month. The pooled analysis revealed that tirzepatide led to -21. At a maintenance dose of 2. 5 mg, 5 mg, 7. The chronic and persistent hyperglycemic state of T2DM. The purpose of the. 5 mL subcutaneous pen injector. The lifestyle intervention included regular lifestyle counselling sessions delivered by a dietitian or qualified health-care professional. 8 lb. , when it was taken at its highest dose in a drug trial. Food and Drug Administration (FDA) approved Eli Lilly and Company's (NYSE: LLY) Zepbound™ (tirzepatide) injection, the first and only obesity treatment of its kind that activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors. Tirzepatide is a first-in-its-drug-class medication for type 2 diabetes. Tirzepatide has a boxed warning (the strictest warning the FDA can give a medication) for thyroid C-cell tumors. All Peptides are shipped non labeled. This translates into 1800mcg which in turn would mean 1. Tirzepatide, a once-weekly injection used to treat type 2 diabetes, also promotes weight loss. The FDA has approved tirzepatide (Mounjaro; Eli Lilly and Company), a novel, dual-targeted treatment shown to improve glycemic control in adults with type 2 diabetes. What are the potential side effects of Tirzepatide? The potential side effects of Tirzepatide include: Nausea: Nausea is a common side effect of GLP-1 receptor agonists, including Tirzepatide. $. Tirzepatide is the first dual GIP/GLP-1 receptor co-agonist approved for the treatment of type 2 diabetes in the USA, Europe, and the UAE. Weeks 13-16+: One Vial of 40mg Mounjaro Injections (Tirzepatide) Inject 10mg once a week. This is where Tirzepatide comes in. Add to Cart. 4% (29. 5 mg) or 15 mg (via steps at 2. 17%. In Eli Lilly's SURMOUNT-1 clinical trial, its experimental obesity drug—a weekly injection called tirzepatide—helped clinical trial patients lose roughly one-fifth of their body weight. Today, the U. I don't think the vyvanse works as well. Severity Graded Adverse Events. 5 mg step), 10 mg (via steps at 2. Introduction and background. ago. 5. It’s easier to use an amount of bac water that splits the doses without much thought. Methods: We systematically. The highest dose of tirzepatide (15 mg) reduced FSG to a greater extent than other doses (5 mg and 10 mg). Semaglutide isn't doing much for me anymore hence I'm switching to Tirzepatide. 5 kg) on 10 mg and 15. It is a 39-amino acid linear synthetic peptide that has been synthesized to mimic the sequence of human (rather than rodent) GIP [Citation 8]. I am currently on 20mg ER daily. 5. 5% Pure. We performed a meta-analysis to assess tirzepatide’s. Tirzepatide is a synthetic analogue of gastric inhibitory polypeptide (GIP) that was developed for its ability to stimulate insulin release and thus address both type 2 diabetes and non-alcoholic fatty liver disease. Lilly will ask the FDA to approve tirzepatide as a weight loss drug. 20 mcg subcutaneously once a day into the thigh or abdominal wall. That was yesterday. Primary analysis showed that tirzepatide 10 mg and 15 mg resulted in more significant reductions in percentage change in body weight than semaglutide 2. 4104 W. GI Side Effect Mitigation: Gradual dose escalation can minimize gastrointestinal side effects like nausea and constipation. S. Tirzepatide is administered subcutaneously once weekly because of its half-life of 5 days. 015625 lbs. 5 mg once-weekly and then increased the dose in a step-wise approach at four-week intervals to their final randomized maintenance dose of 5 mg (via a 2. Tirzepatide Dose: 2. Products and services Proper Use Drug information provided by: Merative, Micromedex ® When you start using this medicine, it is very important that you check. 1 Excess adiposity and its numerous. 01 to 2. INDIANAPOLIS, Nov. Tirzepatide. Because both GLP-1 and GIP are so-called incretin hormones (substances produced in. 6 kg with placebo [57]. Tirzepatide met both co-primary endpoints and all key secondary endpoints compared to placebo for both estimands, with those taking tirzepatide achieving a mean weight reduction of 13. 00 — or Auto-refill and save up to 10% Select options; Semaglutide – Oral $ 399. But it also mimics another incretin called glucose-dependent insulinotropic polypeptide (GIP). humans as the human relevance of tirzepatide-induced . Using only one ml of water minimizes the chance that you will use too much and end up with a bad experience. or 15. 4104 W. Tirzepatide is a synthetic analog of gastric inhibitory polypeptide (GIP) with affinity at glucagon-like receptor-1 (GLP-1). Noopept 20mg/ml @ 30ml; Pramipexole 2mg/ml @ 30ml; RAD-140 10mg/mL @ 30mL; Ralox 50mg/ML @ 30ML; RU-58841 50mg/mL @ 30mL;. INFORMATION. Zepbound contains tirzepatide, also in Eli Lilly’s diabetes drug Mounjaro. Å = Aib, alpha-amino-butyric acid; diacid-γ-Glu(AEFA)2, the linker molecule linking a fatty acid side chain with a length. In clinical trials, weight loss was a. 3 kg) in patients with T2DM. 2 out of 10 from a total of 594 ratings on Drugs. 5 mg for four weeks, once a week (14mg total peptide). 7. tirzepatide 10 mg/0. Come 2030, Cowen expects Novo’s Wegovy sales to top $7 billion, while its full obesity portfolio could reach $14. It is used together with diet and exercise to help control your blood sugar. It is used together with diet and exercise to help control your blood sugar. 07% in the tirzepatide 20 mg group, compared with 0. 8%-14. Study findings. 00 — or Auto-refill and save up to 10% Select options; Gift Card $ 50. Doses of 500mcg or more can be injected with one ml of water. Tirzepatide is administered subcutaneously once weekly because of its half-life of 5 days. Proper Use. The highest dose of tirzepatide (15 mg) reduced FSG to a greater extent than other doses (5 mg and 10 mg). It's contradictory Reply replyTirzepatide was associated with an increased incidence of gastrointestinal adverse events: nausea was the most frequent event with all Tirzepatide doses, especially 15 mg (OR 5. Tirzepatide represents a first-in-class agent for the treatment of T2D. States permitted to ship: WA, OR, ID, UT, AZ, CO, WY, TX, GA, FL Price: $240. For example if you wanted to do 2. The pooled analysis revealed that tirzepatide led to -21. 5 mg, 5 mg, 7. The dosages used in the study were escalated over the first 12 weeks of the trial. 6 kg) Lilly plans to complete rolling submission to the FDA in the coming weeks . 5 mg) or 15 mg (via steps at 2. The decision was made on the same day the US Food and Drug Administration (FDA) approved a version of. Tirzepatide (or matching placebo) was initiated at 2·5 mg once weekly and increased by 2·5 mg every 4 weeks until the target dose was reached (ie, 10 mg or 15 mg at 12 weeks or 20 weeks, respectively). Pharmaceutical experts classify Tirzepatide as an anti-diabetic drug that experts. According to Dr. Once-a-Week Injection: Can be administered through a once-weekly injection. Featured. Each vial (20 mg) will cost $399, plus $46 for overnight shipping. S. Make sure to drink plenty of fluids and stay hydrated if you're experiencing these stomach. November 08, 2023. Tirzepatide is in a class of medications called glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonists. 12 to 10. In addition, tirzepatide is available as reference material for research purposes, and qualified researchers can purchase it from trusted sources. 2 kg) on placebo for the efficacy estimand, which. ICER Publishes Evidence Report on Tirzepatide for Type 2 Diabetes. 3% from study entry after 12 weeks of intensive lifestyle intervention followed by 72 weeks of tirzepatide treatment. 100mg . Usual Adult Dose for Diabetes Type 2. (a hard. 50 Add to cart. If you put 2ml in 10mg vial each 0. The findings indicate tirzepatide may be a potential therapeutic option for individuals living with obesity, with participants losing between 16% and 22. Common side effects may include nausea, vomiting, diarrhea, constipation, upper abdominal discomfort, and abdominal pain. Mounjaro only. 81kg) weight loss (average of the 5mg, 10mg, and 15mg/weekly results) compared to placebo. It is a 39-amino-acid modified peptide based on the GIP sequence. 04% with the placebo). Elevate Your Vitality: Experience a surge in energy, renewed stamina, and laser-sharp focus. 00 Quantity Tirzepatide 40mg Tirzepatide (mounjaro) 10 weeks program from initial dosage. ** Doses per vial (20 mg) 2. 00 – $ 1,000. It's not clear to others because you don't understand it yourself. Mounjaro (tirzepatide) can cause stomach-related side effects (such as nausea, vomiting, diarrhea) that can lead to dehydration. At week 5, the dosage is typically raised to 5 mg once a week for another 4 weeks. Discussion. Tirzepatide is a first-in-its-drug-class medication for type 2 diabetes. 00 — or Auto-refill and save up to 10% Select options; Semaglutide – Oral $ 399. MOUNJARO (tirzepatide) injection, for subcutaneous use, contains tirzepatide, a once weekly GIP receptor and GLP-1 receptor agonist. Terms of sale apply. The Tirzepatide weight loss study, called SURMOUNT-1, evaluated the efficacy and safety of Tirzepatide for weight loss in obese individuals. 4% (29. 00 — or Auto-refill and save up to 10% Select options; Semaglutide – Oral $ 399. Tirzepatide is a once-weekly injectable dual glucose-dependent insulinotropic polypeptide (GIP)/GLP1RA. The once-weekly glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist is indicated as an adjunct to diet and. The Tirzepatide group also had improved cardiovascular and metabolic measures. Tirzepatide is an acylated peptide engineered to activate the GIP and GLP-1 receptors, key mediators of insulin secretion that are also expressed in regions of the brain that regulate food intake. As such, advanced treatment approaches are needed. MOUNJARO (tirzepatide) injection, for subcutaneous use, contains tirzepatide, a once weekly GIP receptor and GLP-1 receptor agonist. (A) The intrinsic potency of TZP (n = 23) in the presence of casein (CAS) is. We aimed to assess efficacy, safety, and tolerability of novel dual glucose-dependent insulinotropic polypeptide and GLP-1 receptor agonist tirzepatide monotherapy versus placebo in. Although the primary. Of the 806 participants enrolled in the study, 579 (71. It is currently. According to statistics, approximately 1 in 11 adults worldwide has diabetes, 90% of whom have T2DM (). SKU: SR-TIRZ Categories: Peptides, USA Peptide Only Tags: Peptide, Peptides, Tirzepatide, USA Peptides. 4mg. Over one-third of participants using tirzepatide achieved weight loss of 25% or more. The proportion of serious AEs was 7. If there is 2ml of liquid in the vial, then the weekly dose of 2. BY PURCHASING THEM YOU AGREE TO USE. 60, 95% CI 3. 5% of their starting weight. The authors found that tirzepatide 15 mg was the most efficacious in reducing HbA1c versus placebo (mean difference -2. 5ml aliquot will be 2. 80mg. Subscribe today!This would mean that in 1. The most common side effects associated with tirzepatide are related to gastrointestinal tract like nausea, vomiting and diarrhea [20,21]. •ZEPBOUND is contraindicated in patients with a personal orTirzepatide Weekly Dose: Initiate at 2. In preclinical models, GIP has been shown to. 0 mg per week = 2 doses ** Derby City Direct Primary Care members will received a discount of $50 per month on Tirzepatide medication. After 4 weeks: The dosage should be increased to 5 mg subcutaneously. Medically reviewed by Dr. 32% with 10 mg and 5. 2. I was on adderall 20mg BID then and it was fine. On Thursday, Eli Lilly released the results of clinical trials involving 2,539 patients, some of whom were given 5 milligram, 10mg or 15mg treatment regimes of the drug. Tirzepatide (Mounjaro) is FDA-approved for lowering blood sugar in people with type 2 diabetes by activating clocose-dependent insulinotropic polypeptide (GIP) and glucagon-like polypeptide (GLP-1) receptors. 1). The efficacy. Those taking 10mgs. Specifically, tirzepatide at 10 mg reduced body weight by 5% or more in 79. Over one-third of participants using tirzepatide. 5 mg SC qWeek x 4 weeks initially; THEN increase to 5 mg SC qWeek. For additional glycemic control: Increase dosage in 2. Tirzepatide/B12 10mg/500mcg – 2mL vial (20mg vial) $ 250. The body weight loss observed in this study opens perspectives for a pharmacological treatment of obesity as an alternative to various procedures of bariatric. Tirzepatide is a promising drug with dual-acting glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor activation that has revolutionized the treatment of type 2 diabetes mellitus (T2DM) as an adjunct to diet and exercise. 2 kg) on placebo for the efficacy estimand, which. Tirzepatide $ 699. Buy Tirzepatide from Peptide Pros, the Best USA SARMs and Peptides for Sale supplier since 2013. 4-mg dose and tirzepatide up to a 15-mg dose, focusing on the Semaglutide Treatment Effect in People with Obesity (STEP) 2, SURPASS-1, and SURPASS-2 trials, the subjects of which were all patients with type 2 diabetes mellitus. About Mounjaro™ (tirzepatide) injection 1 Mounjaro™ (tirzepatide) injection is FDA-approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Weeks 9-12: One Vial of 30mg Mounjaro Injections (Tirzepatide) Inject 7. 30ML Vial with Injection Kit. 5mg, 5mg, 7mg, 10mg, 12. Tirzepatide is available in multiple strengths (2. Based on the above protocol and our preferred vendor's current pricing, here is a breakdown of the total cost per dose on a weekly basis: Weeks 1-4: $82. Tretinoin 45g of 0. Tirzepatide has not been linked to elevations in serum aminotransferase levels during therapy or to episodes of clinically apparent liver injury. 87% with 5 mg of tirzepatide, -1. 57% with 15-mg doses of tirzepatide. Research shows that Semaglutide may also improve heart, liver, and lung function while helping to slow or prevent the effects of Alzheimer’s disease. Tirzepatide, a dual GIP/GLP-1R agonist, demonstrated robust reductions in glycaemic control and body weight for the patients in the SURPASS studies, without causing hypoglycaemia. 25mg subcutaneously once weekly. 5 mg step), 10 mg (via steps at 2. Lilly, the manufacturer of Mounjaro, reported that tirzepatide can help people with type 2 diabetes to lose almost 16% of their body weight. Here are the key findings: Tirzepatide led to A1C reductions of 1. 2. Order: 20 – 49 vials and SAVE 20%. Tirzepatide is based on the human GIP hormone and has a length of 39 amino acids. Mounjaro’s active ingredient tirzepatide was used in the Phase 3 SURMOUNT-1 72-week weight loss clinical trials. 7 h), supporting once-weekly dosing, as compared with approximately 5 and 2 min for GIP and GLP1, respectively [ 1 ]. Get free coupon. This is impressive—and greater. 5ml once reconstituted; or 1ml of bac water and 0. It is given once every week (every 7 days). 4 milligrams weekly. November 08, 2023. Weeks 5-8: 3. 5mg/weekly in weeks 17-20, and 15mg in weeks 21 and beyond. Tirzepatide $ 699. The mean age of participants was 45 years, with 69% female and 71% white. It works by increasing insulin available and decreasing glucagon (a hormone that controls the amount of glucose made by the liver) available in the body. 4 lb. 5Mg/0. 4% and 15. 5mg once a week. Specific AEs were reported by a variable number of studies. 5 mg are not maintenance doses. Generally, the unique aspect of Tirzepatide is that aside from a promising result for the reduction in A1C, It also has synergistic effects in lowering body weight, food. Tirzepatide is a synthetic peptide with glucose-lowering effects. 5 in. 89% with 20 mg of tirzepatide, and -2. Tirzepatide is the first dual GIP/GLP-1 receptor co-agonist approved for the treatment of type 2 diabetes in the USA, Europe, and the UAE. Your entire vial contains 40 mg of tirzepatide & 20 mg of B6. 1, 13. Tirzepatide injection is used to treat type 2 diabetes. To equate the mounjaro 2. Lilly will ask the FDA to approve tirzepatide as a weight loss drug. All participants in the tirzepatide treatment arms started the study at a dose of tirzepatide 2. I liked the switch to ER because it gave me more sustained focus. Buy Mounjaro 2. People usually start with a Mounjaro dosage of 2. 5mg/20mg/0. Takeaway Semaglutide is a drug that can be used for weight. 5mg is half the drug in the vial, so however much you reconstitute with, a 2. This combination allows Tirzepatide to lower blood glucose levels, increase insulin sensitivity, boost feelings of satiety, and accelerate weight loss. 9% weight reduction) by week 12 and were included in the tirzepatide. This product requires monthly dosing step-up. Linebaugh Ave Tampa, FL 33624. 5 × 0. 4mg of semaglutide how much Tirzepatide should I inject?Tirzepatide is at 5 mg every 5 days & for last 2 weeks I’ve added . 00 — or Auto-refill and save up to 10% Select options; Gift Card $ 50. Novo also has an oral semaglutide and three other candidates in its pipeline. It works to stimulate first- and second-phase insulin secretion, and reduces glucagon levels, both in a glucose-dependent manner. Adding 50 units would be fine. 62%). Just ordered 20mg (actually 4x5mg), let's see how it goes. Tirzepatide is a dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1 RA) approved by the US Food and Drug. Tirzepatide is available in multiple strengths (2. Buy 10 for $139. Tirzepatide, also known by its brand name Mounjaro, is the first drug in a new family of medicines that target two hormones — glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) — that are involved in maintaining healthy blood sugar levels, breaking down fat, and reducing appetite by sending signals from the gut to the brain when people are full.